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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11349 | GABAA receptor agent 1 | GABA Receptor | |
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor. | |||
T62426 | GABAA receptor agent 2 TFA | ||
GABAA receptor agent 2 TFA is a potent, high-affinity GABAA receptor antagonist with an IC50 of 24 nM (human α1β2γ2GABAA-expressing tsA201 cells) and a Ki of 28 nM (rat GABAA receptor). GABAA receptor agent 2 TFA has no ... | |||
T61052 | GABAA receptor agent 7 | ||
GABAA receptor agent 7 (compoud 5c) has anticonvulsant activity both in vitro and in vivo with low neurotoxicity which can be used in epilepsy research. GABAA receptor agent 7 is a potent positive modulator of GABAA rece... | |||
T60826 | GABAA receptor agent 8 | ||
GABAA receptor agent 8 (compoud 5e) has the potential in epilepsy research. GABAA receptor agent 8 is a potent positive modulator of GABAA receptor with anticonvulsant activity both in vitro and in vivo as well as low ne... | |||
T60481 | GABAA receptor agent 4 | ||
GABAA receptor agent 4 (compound 1e) is a potent antagonist of γ-GABAAR with Ki of 0.18 µM. GABAA receptor agent 4 has immunomodulatory potential which was shown to efficiently rescue the inhibition of T cell proliferati... | |||
T61668 | GABAA receptor agent 5 | ||
GABAA Receptor Agent 5 (compound 018) serves as a potent γ-GABAAR antagonist, possessing a Ki of 0.020 μM. This compound exhibits γ-GABAAR antagonist properties, yet it demonstrates low cellular membrane permeability [1]... | |||
T60817 | GABAA receptor agent 6 | ||
GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with low cellular membrane permeability (Ki = 0.56 μM) [1]. | |||
T22509 | 3-Methyl-GABA | Others | |
3-Methyl-GABA, an anticonvulsant agent [1] [2], acts as a potent activator of GABA aminotransferase, fits the binding pocket of the GABA A receptor (GABAaR), and activates L-glutamic acid decarboxylase (GAD). |