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Search Results for " gabaa receptor agent-1 "

8

Compounds

Cat No. Product Name Synonyms Targets
T11349 GABAA receptor agent 1 GABA Receptor
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
T62426 GABAA receptor agent 2 TFA
GABAA receptor agent 2 TFA is a potent, high-affinity GABAA receptor antagonist with an IC50 of 24 nM (human α1β2γ2GABAA-expressing tsA201 cells) and a Ki of 28 nM (rat GABAA receptor). GABAA receptor agent 2 TFA has no ...
T61052 GABAA receptor agent 7
GABAA receptor agent 7 (compoud 5c) has anticonvulsant activity both in vitro and in vivo with low neurotoxicity which can be used in epilepsy research. GABAA receptor agent 7 is a potent positive modulator of GABAA rece...
T60826 GABAA receptor agent 8
GABAA receptor agent 8 (compoud 5e) has the potential in epilepsy research. GABAA receptor agent 8 is a potent positive modulator of GABAA receptor with anticonvulsant activity both in vitro and in vivo as well as low ne...
T60481 GABAA receptor agent 4
GABAA receptor agent 4 (compound 1e) is a potent antagonist of γ-GABAAR with Ki of 0.18 µM. GABAA receptor agent 4 has immunomodulatory potential which was shown to efficiently rescue the inhibition of T cell proliferati...
T61668 GABAA receptor agent 5
GABAA Receptor Agent 5 (compound 018) serves as a potent γ-GABAAR antagonist, possessing a Ki of 0.020 μM. This compound exhibits γ-GABAAR antagonist properties, yet it demonstrates low cellular membrane permeability [1]...
T60817 GABAA receptor agent 6
GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with low cellular membrane permeability (Ki = 0.56 μM) [1].
T22509 3-Methyl-GABA Others
3-Methyl-GABA, an anticonvulsant agent [1] [2], acts as a potent activator of GABA aminotransferase, fits the binding pocket of the GABA A receptor (GABAaR), and activates L-glutamic acid decarboxylase (GAD).
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